Drug projects fail constantly

  • The estimated average pre-tax industry cost per new prescription drug approval (inclusive of failures and capital costs) is $2.6 billion.1
  • The processes of discovery and clinical trials amounts to approximately 12 years from research lab to the patient.
  • For every 25,000 compounds that start in the laboratory, 25 are tested in humans, 5 make it to market and just one recoups what was invested.2
  • Around 90% of all compounds that start in the clinic never make it out. Drug projects fail constantly.3

Simmaren develops software to help researchers design more efficient and safer drugs, and reduce cost and the risk of failure in the clinical phase.


1. Joseph A. DiMasia, Henry G. Grabowskib, Ronald W. Hansen, Innovation in the pharmaceutical industry: New estimates of R&D costs. Journal of Health Economics 2016, 47, 20–33. Link
2. The Pharmaceutical Journal, PJ March 2015 online. Link
3. FDA. 22 case studies where phase 2 and phase 3 trials had divergent results. 2017. Link